ADVANCES IN TRANS-EPITHELIAL ELECTRICAL RESISTANCE (TEER) MONITORING INTEGRATION IN AN INTESTINAL BARRIER-ON-CHIP (IBOC) PLATFORM WITH MICROBUBBLES-TOLERANT ANALYTICAL METHOD

Advances in Trans-Epithelial Electrical Resistance (TEER) monitoring integration in an Intestinal Barrier-on-Chip (IBoC) platform with microbubbles-tolerant analytical method

Trans-epithelial resistance (TEER) is one of the most widely performed analysis in vitro methods for monitoring barrier tissue development, formation and functional maturation.It is a basic PULSE SNSR and important tool for the reproduction of an artificial human epithelium.However, in the design and construction of organ on chip devices, the relia

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Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes

Cytolytic T cell responses are predicted to be biased towards membrane proteins.The peptide-binding grooves of most alleles of histocompatibility complex class I (MHC-I) are relatively hydrophobic, therefore peptide Dryer Motor Pulley fragments derived from human transmembrane helices (TMHs) are predicted to be presented more often as would be expe

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